The purpose of this Test Guideline is to determine the effects on the reproduction of a substance administered with food to birds.Birds are fed a diet containing the test substance in various concentrations for a period of not less than 20 weeks. A minimum of three dietary concentrations of the...

The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed for use with the rat. It is recommended that...

The purpose of this Test Guideline is to determine the effects of a substance administered with food to birds. Birds are fed a diet containing the test substance at a range of concentrations for a period of five days. Two control groups and one treatment group for each of the, at least, five...

This Test Guideline describes the Zahn-Wellens/EMPA Test. It is used to determine inherent biodegradability. A mixture containing the non-volatile and water soluble test substance, mineral nutrients and a relatively large amount of activated sludge in aqueous medium is agitated and aerated at...

This test measures chromosome events in spermatogonial germ cells and is, therefore, expected to be predictive of induction of inheritable mutations in germ cells. Male Chinese hamsters and mice are commonly used. Animals are exposed to the test substance (liquid or solid) by an appropriate...

This Test Guideline describes a method to assess effects of a test chemical on the phagocytotic activity of activated sludge containing protozoan organisms under defined conditions in the presence of different concentrations of the test chemical. The principle of biological sewage-treatment...

This Test Guideline is a laboratory test method, designed to assess the acute contact toxicity of pesticides and other chemicals to adult worker honeybees. Anaesthetized adult worker honeybees are exposed to five doses in a geometric series of the test substance dissolved in appropriate carrier...

This Test Guideline is designed to assess the effects of prolonged exposure of chemicals to the sediment-dwelling larvae of the freshwater dipteran Chironomus sp. First instar chironomid larvae are exposed to at least five concentrations of the test chemical in sediment - water systems. The test...