Objectives To conduct pooled estimates and comparative evaluations of safety and efficacy, alongside cost-effectiveness and value-based pricing analyses, for systemic treatments recommended by the National Comprehensive Cancer Network in refractory colorectal cancer. Methods A comprehensive...

Three years ago, ERSTE Foundation, Erste Group and the University of Tartu decided to try out something new: changing perspective to explore financial well-being through a human lens. At ERSTE Foundation, we aim to understand what prosperity means to individuals and our societies and how our...

Vor drei Jahren beschlossen wir gemeinsam mit der Erste Group und der Universität Tartu, etwas Neues auszuprobieren: eine neue Perspektive einzunehmen und finanzielles Wohlbefinden vom Menschen ausgehend zu beleuchten. Wir bei der ERSTE Stiftung wollen verstehen, was Wohlstand für den oder die...

This study examines three key research questions related to altruistic and egoistic motivations for sustainable behavior. It explores whether altruism is an intrinsic characteristic or context-dependent, if the distinction between altruism and egoism should be modeled as a binary or a continuum,...

Using simulated patients to mimic nine established non-communicable and infectious diseases over 27 trials, we assess ChatGPT's effectiveness and reliability in diagnosing and treating common diseases in low- and middle-income countries. We find ChatGPT's performance varied within a single...

Using simulated patients to mimic nine established non-communicable and infectious diseases over 27 trials, we assess ChatGPT's effectiveness and reliability in diagnosing and treating common diseases in low- and middle-income countries. We find ChatGPT's performance varied within a single...

Seafarer fatigue as a risk factor in ship operations has gained attention in the maritime industry and research. The aim of this review is therefore to analyse the current state of knowledge based on literature from 2008 to 2023 and, in particular, to identify relevant influencing factors. The...

The paper presents the results of a study on work-related values of Generation Z, comprised of young people born between the late 1990s and 2010. Following Millennials, Generation Z is the first generation of digital natives. This is the reason, along with some other circumstances that...

Background: For several years, two of the major concerns of logistics managers are (i) the visibility of global supply chains and (ii) the uncertainty in deciding which existing logistics security program is the most appropriate according to the security levels for their organization. This last...

Using simulated patients to mimic nine established non-communicable and infectious diseases over 27 trials, we assess ChatGPT's effectiveness and reliability in diagnosing and treating common diseases in low- and middle-income countries. We find ChatGPT's performance varied within a single...

Im maritimen Raum findet sich eine Vielzahl von Infrastrukturen, die von zentraler Bedeutung für die globalen Energiebeziehungen, das Netz des weltweiten Handels mit Nahrungs- und Düngemitteln und nicht zuletzt den Datenaustausch im Internet sind. Schon immer war das Meer Austragungsort...

Using simulated patients to mimic nine established non-communicable and infectious diseases over 27 trials, we assess ChatGPT's effectiveness and reliability in diagnosing and treating common diseases in low- and middle-income countries. We find ChatGPT's performance varied within a single...

Over the past decades, US Congress enabled the US Food and Drug Administration (FDA) to facilitate and expedite drug development for serious conditions filling unmet medical needs with five special designations and review pathways: orphan, fast track, accelerated approval, priority review, and...

Purpose Railways are a well-known example of complex critical infrastructure, incorporating socio-technical systems with humans such as drivers, signallers, maintainers and passengers at the core. The technological evolution including interconnectedness and new ways of interaction lead to new...

We study whether it is socially desirable to hold a monopolistic firm liable for the harm its potentially judgment-proof consumers inflict on third parties. Consumers' judgment-proofness limits potential product differentiation by pooling different consumer types with uniform liability exposure....

Background: Over the past decades, US Congress enabled the US Food and Drug Administration (FDA) to facilitate and expedite drug development for serious conditions filling unmet medical needs with five special designations and review pathways: orphan, fast track, accelerated approval, priority...

Replacing car travel with walking and cycling lowers emissions, improves air quality and makes communities healthier. Rates of active travel typically increase when dedicated infrastructure is implemented. But policymakers in multiple countries regularly contend with two obstacles: designing...

Workplace abuse is a widespread, worldwide social phenomenon and the topic is highly germane, given the established link between employment quality and mental and physical health and the changes developing in the labor market, including globalization processes, economic recession influenced by...

Background: Over the past decades, US Congress enabled the US Food and Drug Administration (FDA) to facilitate and expedite drug development for serious conditions filling unmet medical needs with five special designations and review pathways: orphan, fast track, accelerated approval, priority...

Purpose - Drawing on self-concept theory, this study evaluates the mediating effects of employees' psychological states on the relationship between human resources (HR) practices and employee engagement. Design/methodology/approach Through random sampling, 434 customer-contact frontline...

The purpose of this Special Issue is to show progress regarding current research and literature on the theme of "Current Trends in Tourism under COVID-19 and Future Implications for Sustainability". In particular, this Special Issue of the peer-reviewed international journal Sustainability...

Replacing car travel with walking and cycling lowers emissions, improves air quality and makes communities healthier. Rates of active travel typically increase when dedicated infrastructure is implemented. But policymakers in multiple countries regularly contend with two obstacles: designing...