An unusual antagonistic pleiotropy in the Penna model for biological ageing

We combine the Penna Model for biological ageing, which is based on the mutation-accumulation theory, with a sort of antagonistic pleiotropy. We show that depending on how the pleiotropy is introduced, it is possible to reproduce both the humans mortality, which increases exponentially with age, and fruitfly mortality, which decelerates at old ages, allowing the appearance of arbitrarily old Methuselah's.

MoreLess

Year of publication:	2001
Authors:	Sousa, A.O ; Moss de Oliveira, S
Published in:	Physica A: Statistical Mechanics and its Applications. - Elsevier, ISSN 0378-4371. - Vol. 294.2001, 3, p. 431-438
Publisher:	Elsevier
Subject:	Ageing \| Penna model \| Monte carlo simulations

More details

Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://www.econbiz.de/10010590704