Exploratory analysis of single nucleotide polymorphism (SNP) for quantitative traits

With the decreasing cost and the increasing ability to quickly genotype single nucleotide polymorphisms (SNP) across the human genome, large databases containing possibly hundreds of typed SNPs are becoming common in populationbased studies of quantitative traits. Testing for association between individual SNPs and the quantitative trait is an important first step in the discovery of disease susceptibility SNPs. This task, however, could be time-consuming and tediousifalargenumberofSNPs is involved. In this article, I introduce two new commands designed to facilitate the screening and testing of multiple SNPsfor possible association with quantitative traits. Copyright 2005 by StataCorp LP.