Normalization of Dye Bias in Microarray Data Using the Mixture of Splines Model

This paper discusses characteristics of dye biases in microarray data that the conventional normalization methods do not handle, and proposes a new normalization method involving a mixture of splines model. We also develop a test for between-group comparisons of each gene that is designed to be used with our proposed method.

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Year of publication:	2007
Authors:	Joo, Yongsung ; Casella, George ; Booth, James ; Lee, Keunbaik ; Enkemann, Steven
Published in:	Statistical Applications in Genetics and Molecular Biology. - Berkeley Electronic Press. - Vol. 6.2007, 1, p. 2-2
Publisher:	Berkeley Electronic Press
Subject:	mixture of splines \| microarray data \| dye bias

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Extent:	application/pdf
Type of publication:	Article
Notes:	oai:bepress:
Source:	RePEc - Research Papers in Economics

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