Simulation is widely used to investigate real-world systems in a large number of fields, including clinical trials for drug development, since real trials are costly, frequently fail and may lead to serious side effects. This paper is a survey of the statistical issues arising in these simulated...

This paper describes some analytic simulation experiments performed on a nonlinear macroeconometric model of the Italian economy. The proposed techniques extend to nonlinear models methods that are available, in the literature, for linear econometric models. The results can be profitably used...

Operational validation of a linear programming model of a dairy farm is done on the basis of representative results from reality. The model will be used to determine the effects of institutional, technical and price changes on the results of dairy farms. Average results of specialized dairy...