We consider the classical problem of selecting the best of two treatments in clinical trials with binary response. The target is to find the design that maximizes the power of the relevant test. Many papers use a normal approximation to the power function and claim that Neyman allocation that...

This paper is concerned with hierarchical data having three levels. The level 1 units are nested in the level 2 units or subclusters which are themselves nested in the level 3 clusters. The model for this data is assumed to fulfill some symmetry assumptions. The level 1 units within each...

A semiparametric approach to the one-way layout is described, and its efficiency in the two-sample case relative to the common t-test is studied. The power efficiency computed for several special cases points to an intriguing behaviour where one test may be more efficient than the other over a...

In this paper the asymptotic Pitman efficiencies of the affine invariant multivariate analogues of the rank tests based on the generalized median of Oja are considered. Formulae for asymptotic relative efficiencies are found and, under multivariate normal and multivariatetdistributions, relative...