Meta-analysis of diagnostic test accuracy presents many challenges. Even in the simplest case, when the data are summarized by a 2 × 2 table from each study, a statistically rigorous analysis requires hierarchical (multilevel) models that respect the binomial data structure, such as...

Group size is an essential aspect of experiments using group testing. In this study, we establish the relationship of the optimal group size to the proportion p. Two robust estimators are proposed and investigated through simulations.

In diagnostic studies, the receiver operating characteristic (ROC) curve and the area under the ROC curve are important tools in assessing the utility of biomarkers in discriminating between non-diseased and diseased populations. For classifying a patient into the non-diseased or diseased group,...