Abstract Mann–Whitney-type causal effects are clinically relevant, easy to interpret, and readily applicable to a wide range of study settings. This article considers estimation of such effects when the outcome variable is a survival time subject to right censoring. We derive and discuss...

Background In the last decade, network meta-analysis of randomized controlled trials has been introduced as an extension of pairwise meta-analysis. The advantage of network meta-analysis over standard pairwise meta-analysis is that it facilitates indirect comparisons of multiple interventions...

This is the first indirect meta-analysis in RA that compares the efficacy and safety of biosimilar-infliximab to the other biologicals indicated in RA. We found no significant difference between infliximab-biosimilar and other biological agents in terms of clinical efficacy and safety. </AbstractSection>...

The economic literature on cost-effectiveness analysis in the context of decisions by health technology assessment agencies assumes as the quantity of interest a linear combination of the mean of the sampling distribution of the effectiveness and the cost. We argue that this is not always...

Thesis (Ph.D.)--University of Rochester. School of Medicine and Dentistry. Dept. of Biostatistics and Computational Biology, 2009.