Technological advances make it possible to use high-throughput sequencing as a primary discovery tool of medical genetics, specifically for assaying rare variation. Still this approach faces the analytic challenge that the influence of very rare variants can only be evaluated effectively as a...

DNA Fragment Assembly (DFA) is a process of finding the best order and orientation of a set of DNA fragments to reconstruct the original DNA sequence from them. As it has to consider all possible combinations among the DNA fragments, it is considered as a combinatorial optimisation problem. This...

The adoption of cloud computing for engineering and scientific applications is still lagging behind, although many cloud providers today offer powerful computing infrastructure as a service, and enterprises are already making routine use of it. Reasons for this slow adoption are many: complex...

A healthy liver leads to healthy life. In India, as well as in other parts of the world, liver disease is one of the principle areas of concern in medicine. For this study, diagnosis of liver disease is performed by deploying classification methods include linear discriminant analysis (LDA),...

A general function to quantify the weight of evidence in a sample of data for one hypothesis over another is derived from the law of likelihood and from a statistical formalization of inference to the best explanation. For a fixed parameter of interest, the resulting weight of evidence that...