Search Results - subject:"matched case-control study"

Bias Reduction and Goodness-of-Fit Tests in Conditional Logistic Regression Models

Sinha, Samiran (contributor); Wang, Suojin (contributor) - 2010

This dissertation consists of three projects in matched case-control studies. In the firstproject, we employ a general bias preventive approach developed by Firth (1993) to handlethe bias of an estimator of the log-odds ratio parameter in conditional logistic regression bysolving a modified...

Persistent link: https://www.econbiz.de/10009464883

Inference of the Haplotype Effect in a Matched Case-Control Study Using Unphased Genotype Data

Sinha, Samiran; Gruber, Stephen; Mukherjee, Bhramar; … - In: International Journal of Biostatistics 4 (2008) 1, pp. 1079-1079

-control design. There are several methods for estimating a disease-haplotype association parameter in a matched case-control study … genotype data arising from a matched case-control study design. The proposed method relies on a logistic disease risk model and … matched case-control study of breast cancer patients conducted in Israel. The performance of the proposed method is evaluated …

Persistent link: https://www.econbiz.de/10005585153