Dette, Holger; Pepelyshev, Andrey; Wong, Weng Kee - Institut für Wirtschafts- und Sozialstatistik, … - 2008
We construct optimal designs for estimating fetal malformation rate, prenatal death rate and an overall toxicity index in a toxicology study under a broad range of model assumptions. We use Weibull distributions to model these rates and assume that the number of implants depend on the dose...
