For many problems of statistical inference in regression modelling, the Fisher information matrix depends on certain nuisance parameters which are unknown and which enter the model nonlinearly. A common strategy to deal with this problem within the context of design is to construct maximin...

The problem of constructing standardized maximin D-optimal designs for weighted polynomial regression models is addressed. In particular it is shown that, by following the broad approach to the construction of maximin designs introduced recently by Dette, Haines and Imhof (2003), such designs...

We derive strong uniform approximations for the eigenvalues in general Laguerre and Hermite beta-ensembles by showing that the maximal discrepancy between the suitably scaled eigenvalues and roots of orthogonal polynomials converges almost surely to zero when the dimension converges to infinity....

Toxicologists have been increasingly using a class of models to describe a continuous response in the last few years. This class consists of nested nonlinear models and is used for estimating various parameters in the models or some meaningful function of the model parameters. Our work here is...

In the problem of testing the equality of k regression curves from independent samples we discuss three methods using nonparametric estimation techniques of the regression function. The first test is based on a linear combination of estimators for the integrated variance function in the...

In the common nonparametric regression model y(i) = g(ti) + a (ti) ei , i=1….,n with i.i.d - noise and nonrepeatable design points ti we consider the problem of choosing an optimal design for the estimation of the regression function g. A minimax approach is adopted which searches for designs...