Methoden um die genetische Information von Organismen gezielt zu verändern sind im Begriff die Biologie und Medizin zu revolutionieren. Die neuste dieser Methoden, die sogenannte CRISPR-Technologie, vereint hohe Effizienz und Genauigkeit mit großer Einfachheit in der Anwendung. Diese Studie...

CRISPR, a breakthrough technology that can modify or screen DNA in almost any organism, has profoundly influenced innovation in a range of applications. Recognizing the importance of CRISPR, the 2020 Nobel Prize winning technology, the EFI commissioned this project to map the research,...

Der vorliegende Bericht an die Expertenkommission Forschung und Innovation untersucht Rechtsfragen, die sich im Kontext der Genomeditierung am Menschen stellen. Den Ausgangspunkt bildet eine vergleichende Analyse der Regulierung in Deutschland, Frankreich, Großbritannien, der Schweiz, den...

In this note, I address the trade-off between children's health and parental preference toward similarity with children. In my model, better-off individuals mate genetically close partners and then use wealth to treat their children's health problems, caused by inbreeding depression. As a...

Educational attainment (EA) is influenced by characteristics other than cognitive ability, but little is known about the genetic architecture of these "non-cognitive" contributions to EA. Here, we use Genomic Structural Equation Modelling and prior genome-wide association studies (GWASs) of EA...

We empirically assess the potential financial impact of future gene therapies on the US economy. After identifying 109 late-stage gene therapy clinical trials currently underway, we estimate the number of new and existing patients with corresponding diseases to be treated by these gene...

Biologics accounted for roughly $145 billion in spending in 2018 (IQVIA, 2019). They are also the fastest growing segment of the pharmaceutical industry. The Biological Price Competition and Innovation Act (BPCIA) of 2010 created an abbreviated pathway for biosimilar products to promote price...

This article is about the need for more and more nutritious food, the potential genetic engineering technology has to contribute to a solution, the fact that this potential is blocked by regulation, which to my understanding is totally unjustified.

Recent advances have led to the discovery of specific genetic variants that predict educational attainment. We study how these variants, summarized as a genetic score variable, are associated with human capital accumulation and labor market outcomes in the Health and Retirement Study (HRS). We...

Recent advances in behavioral genetics have enabled the discovery of genetic scores linked to a variety of economic outcomes, including education. We build on this progress to demonstrate that the same genetic variants that predict educational attainment independently predict household wealth in...

"As development donors invest hundreds of millions of dollars into improved crops designed to alleviate poverty and hunger, Africa has emerged as the final frontier in the global debate over agricultural biotechnology. The first data-driven assessment of the ecological, social, and political...

This dissertation explores the ways in which genetically modified (GM) cotton seeds, rice seeds, and organic cotton seeds in Telangana, India set farmers on diverging economic, environmental, and social trajectories. GM cotton, a cash crop sold under hundreds of different brand names by private...

Networked technonationalism in the biomedical industry : mapping the global innovation and market context -- Knowledge and network typology : comparing national innovation systems and entrepreneurial ecosystems -- Classic technonationalism in Japan : beyond the "miracle" and "lost" decades --...

Recent advances have led to the discovery of specific genetic variants that predict educational attainment. We study how these variants, summarized as a genetic score variable, are associated with human capital accumulation and labor market outcomes in the Health and Retirement Study (HRS). We...

Gene editing techniques represent a major advance in the field of biotechnological research and application, promising significant benefits across the domains of human health, sustainability and the economy. There is broad agreement that gene editing techniques go beyond incremental advances of...

Gene editing aims to modify the genetic sequence at a precise genomic location. Recent breakthroughs in gene editing techniques such as the clustered regularly interspaced short palindromic repeats (CRISPR) system have ushered in a new era for gene editing and health innovation. The purpose of...

Lebensmittel müssen auf Grundlage bestehender EU-Vorschriften gekennzeichnet werden, wenn das Lebensmittel oder einer der verwendeten Inhaltsstoffe gentechnisch verändert oder aus einem gentechnisch veränderten Organismus hergestellt ist. Dabei ist es unerheblich, ob die gentechnische...

Lebensmittel müssen auf Grundlage bestehender EU-Vorschriften gekennzeichnet werden, wenn das Lebensmittel oder einer der verwendeten Inhaltsstoffe gentechnisch verändert oder aus einem gentechnisch veränderten Organismus hergestellt ist. Dabei ist es unerheblich, ob die gentechnische...

Lebensmittel müssen auf Grundlage bestehender EU-Vorschriften gekennzeichnet werden, wenn das Lebensmittel oder einer der verwendeten Inhaltsstoffe gentechnisch verändert oder aus einem gentechnisch veränderten Organismus hergestellt ist. Dabei ist es unerheblich, ob die gentechnische...

Do transgenic crops cause agrobiodiversity erosion? We hypothesize that they increase productivity and reduce production risk and may therefore reduce farmer demand for on-farm varietal diversity, especially when only a few transgenic varieties are available. We also hypothesize that varietal...

Recently the sequencing of the human genome has become a major biological and clinical research field. However, the public health impact of this new technology with focus on the financial effect is not yet to be foreseen. To provide an overview of the current health economic evidence for genome...