CAT-ClinART will establish a regional structure for Radiotherapy clinical audits in Catalonia. The project includes the implementation of a specialized training course, the development of the methodology and essential infrastructure to support clinical audits and a pilot test in all radiotherapy...

The rapid development of AI solutions reveals opportunities to address the underdiagnosis and poor management of chronic conditions in developing settings. Using the method of simulated patients and experimental designs, we evaluate the quality, safety, and disparity of medical consultation with...

Natural products have always played an important part in cancer treatment. These chemicals are generally obtained from plants and microbes, which are significant sources of bioactive molecules with strong anticancer effects. Plant-derived anticancer drugs include Cisplatin, Taxanes, Gemcitabine,...

Background Clinical guidelines recommend surgery for early-stage breast cancer in operable patients; however, primary endocrine therapy (PET) is often used in older women aged ≥ 70. This study aimed to estimate the cost-effectiveness and value of implementation of surgery plus adjuvant...

Over the past decades, US Congress enabled the US Food and Drug Administration (FDA) to facilitate and expedite drug development for serious conditions filling unmet medical needs with five special designations and review pathways: orphan, fast track, accelerated approval, priority review, and...

Two in five Americans have medical debt, nearly half of whom owe at least $2,500. Concerned by this burden, governments and private donors have undertaken large, high-profile efforts to relieve medical debt. We partnered with RIP Medical Debt to conduct two randomized experiments that relieved...

Background Recently, the endovascular treatment (EVT) of acute ischemic stroke has made significant progress in many aspects. Intravenous thrombolysis (IVT) is usually recommended before endovascular treatment in clinical practice, but the value of the practice is controversial. The latest...

Recent work by Kleshnina et al. has presented a Stackelberg evolutionary game model in which the Stackelberg equilibrium strategy for the leading player corresponds to the optimal cancer treatment. We present an approach that is able to quickly and accurately solve the model presented in that work.

We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients. We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical guideline change in Denmark. Using administrative...

We investigate the effects of radiation therapy on the mortality and economic outcomes of breast cancer patients.We implement a 2SLS strategy within a difference-in-difference framework exploiting variation in treatment stemming from a medical guideline change in Denmark. Using administrative...

The Marrakesh Agreement Establishing the World Trade Organization (WTO) allows WTO Members to agree to temporarily waive obligations under the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement). However, the TRIPS Decision adopted by the 12th WTO Ministerial...

Can information about the value of diagnostic tests improve provider practice and help patients recognize higher quality of care In a randomized experiment at public clinics in Mali, health providers and patients received tailored information about the importance of rapid diagnostic tests (RDTs)...

Housing and health are critical issues for policymakers and the public. Secure and affordable housing, along with quick access to required health and social care, are considered essential services for the public and are key targets for planners. In Ireland, as in many countries, the need to...

Healthcare sensor data analytics : foundational concepts, architecture, data analysis techniques, data quality, errors, and applications / G.S. Karthick -- Statistical approximation of streaming sensor data for enhancing healthcare analytics / Aadharsh B, Arunpriya C -- Sensor data analytics for...

Mental illness exacts a heavy toll on the US healthcare system and strains general hospitals and their emergency departments. We study how psychiatric inpatient facility entry impacts the local hospital industry. We find that referrals, including from the legal system, are redirected to the...

We deployed large language model (LLM) decision support for health workers at two outpatient clinics in Nigeria. For each patient, health workers drafted care plans that were optionally revised after LLM feedback. We compared unassisted and assisted plans using blinded randomized assessments by...

There is evidence that physicians disproportionately suffer from substance use disorder and mental health problems. It is not clear, however, whether these phenomena are causal. We use data on Dutch medical school applicants to examine the effects of becoming a physician on prescription drug use...

Objective By manipulating patients' critical attitude in a video experiment, we examined whether physicians are more intended to perform defensive acts because of a higher perceived liability risk in Belgium. Methods We assigned 85 practicing gynaecologists/obstetricians and orthopaedists...

Background The escalating prevalence of type 2 diabetes (T2DM) poses an unparalleled economic catastrophe to developing countries. Cardiovascular diseases remain the primary source of costs among individuals with T2DM, incurring expenses for medications, hospitalizations, and surgical...

Capitalizing a Cure takes us into the struggle over accessing a medical breakthrough to investigate the power of finance over business, biomedicine, and public health. When sofosbuvir-based medicines launched in 2013, they promised a cure for millions of patients worldwide with hepatitis C. But...