An adaptive design for clinical trials with non-dichotomous response and prognostic factors

We present an adaptive design for multi-arm clinical trials with bounded response and prognostic factors. The allocation is ruled by an urn model that fits a Robbins-Monro scheme. We obtain asymptotic properties for the performance and allocation of treatments.

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Year of publication:	2006
Authors:	Moler, José A. ; Plo, Fernando ; San Miguel, Miguel
Published in:	Statistics & Probability Letters. - Elsevier, ISSN 0167-7152. - Vol. 76.2006, 17, p. 1940-1946
Publisher:	Elsevier
Keywords:	Adaptive designs Urn models Robbins-Monro Algorithm Asymptotic limits

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Type of publication:	Article
Source:	RePEc - Research Papers in Economics

Persistent link: https://www.econbiz.de/10005259022