Analyzing an Innovative Environment: San Diego as a Bioscience Beachhead

This article examines dynamics underlying the growth of a flourishing bioscience cluster in San Diego, California, to illustrate the construction of an innovative environment and the matching of place characteristics with a specific economic activity. Extensive interviews explore the formation of synergistic connections promoting the political, economic, and social networks of entrepreneurial individuals at the metropolitan scale. Spatial proximity is shaped by real estate considerations within and between local clusters in a volatile industry affected strongly by shifting access to financial and human capital. Five key factors underlying regional success are found to be access to an outstanding research university, advocacy leadership, risk financing, an entrepreneurial culture, and appropriate real estate, knit by an intensive information exchange network.