Although the Asia-Pacific region has made significant progress towards the Millennium Development Goals (MDGs), most of its countries are still off-track on one or more indicators. This policy brief examines what would it take for countries in the Asia-Pacific region to meet their MDG targets by 2015. It first focuses on the income-poverty gap which continues to persist despite high rates of growth. It then goes on to provide estimates of the resources needed for closing the MDG gaps in the areas of education, health, nutrition and sanitation. It concludes with a few remarks on policy challenges in the light of the findings.