This study aimed to investigate the effect of fungal (Penicillium chrysogenum, Thielavia basicola, and Curvularia hawaiiensis) and bacterial (Sphingomonas aquatilis, Bacillus licheniformis, Exiguobacterium aurantiacum, Micromonospora echinaurantiaca, and Kocuria rhizophila) endophytes and their interaction on some growth and physiological traits of tomato plant (Solanum Lycopersicum L.) cultivar 8320 under greenhouse conditions. To do this, tomato seeds inoculated by fungal and bacterial endophytes were planted in seedling trays in the greenhouse of Hormozgan University in 2019. The experiment was performed in a completely randomized design with three fungal and five bacterial entophytic treatments and their interaction with three replications in which traits such as fresh and dry stem weight, stem height, relative leaf water content, chlorophyll fluorescence, chlorophyll a, chlorophyll b, carotenoid, antioxidant activity, phenol, proline, and total carbohydrate contents were measured. The results showed that fungal and bacterial endophytes and their interaction significantly increased the fresh and dry weight of stem, stem height, chlorophyll fluorescence, chlorophyll a, chlorophyll b, carotenoids, relative leaf water content, antioxidant activity, phenol, proline, and total carbohydrate contents. A complication of both endophytes had a synergistic effect on the above-mentioned traits compared with their separate application. In general, it can be concluded that the symbiosis of endophytes Thielavia basicola + Penicillium chrysogenum, Sphingomonas aquatilis + Micromonospora echinaurantiaca, Penicillium chrysogenum + Micromonospora echinaurantiaca, and Penicillium chrysogenum + Exiguobacterium aurantiacum in a clever combination with tomato plants would increase the morphophysiological attributes of the plants. This issue may help plants to enhance their capability to cope with biotic and abiotic stresses
