Quality of Life Therapy and Coaching (also known as Quality of Life Therapy) is a comprehensive, manualized, theory-based, and, according to Diener (2013) and Seligman (Flourish, Free Press, NY, <CitationRef CitationID="CR134">2011</CitationRef>, p. 292), evidence-based approach to well being, happiness, and positive psychology intervention suitable for both coaching and clinical applications. Clients are taught strategies and skills aimed at helping them to identify, pursue, and fulfill their most cherished needs, goals, and wishes in sixteen valued areas of life said to comprise human well-being and happiness. Quality of Life Therapy and Coaching is “manualized” in the form of the book entitled Quality of Life Therapy (Frisch <CitationRef CitationID="CR57">2006</CitationRef>), providing step-by-step instruction in assessing well-being, tailoring interventions, and monitoring progress, outcome, and follow-up with the evidence-based well-being assessment, the Quality of Life Inventory or QOLI<Superscript>®</Superscript>. This article describes Quality of Life Therapy and Coaching and reviews developments and research since the publication of the manual in 2006. Randomized controlled trials bearing on the empirical support of Quality of Life Therapy and Coaching and the related assessment, the Quality of Life Inventory, are reviewed. The steps in Quality of Life Therapy and Coaching are delineated in the context of an illustrative case and an underlying theory which attempts to integrate findings from the fields of well-being, positive psychology, happiness, quality of life, social indicators research, psychotherapy, and coaching. Future applications and research are suggested which may identify the effective components of Quality of Life Therapy and Coaching and assess their direct impact on health and illness, encourage the use of evidence-based assessments and interventions on the part of well being coaches and therapists, and create health care delivery systems in which well being assessments and interventions are conducted concurrently with symptom-oriented tests and treatments. Copyright Springer Science+Business Media B.V. 2013
