Likelihood inference for discretely observed non-linear diffusions

This paper is concerned with the Bayesian estimation of non-linear stochastic differential equations when only discrete observations are available. The estimation is carried out using a tuned MCMC method, in particular a blocked Metropolis-Hastings algorithm, by introducing auxiliary points and using the Euler-Maruyama discretisation scheme. Techniques for computing the likelihood function, the marginal likelihood and diagnostic measures (all based on the MCMC output) are presented. Examples using simulated and real data are presented and discussed in detail.