Place effects for areas defined by administrative boundaries: A life course analysis of mortality and cause specific morbidity in Scania, Sweden

To understand the origin of disease risk in adulthood, factors in all stages of life and on different contextual levels should be considered. Therefore, the aim of this study was to investigate the relevance of a person’s area of residence over their life course with regard to four outcomes: all-cause mortality; ischemic heart disease mortality and morbidity; cancer mortality and morbidity; and respiratory diseases and related mortality. We applied a cross-classified multilevel model for three age groups on a longitudinal data set spanning a 35 year period in Scania, Sweden. According to our analyses, the proportion of the total variance at the district level for all the outcomes studied was below 2% for the 65 to 84 age group, below 4.5% for those ages 50–64 years, and below 6.5% for those 30–49 years old.