Simulating Lifetime Outcomes Associated with Complications for People with Type 1 Diabetes

The model incorporates diabetic complications risk data from a type 1 diabetes population and synthesizes other type 1—specific data to estimate long-term outcomes of CVD, end-stage renal disease, LEA and risk of blindness, along with life expectancy and QALYs. External validation was carried out using life expectancy and absolute risk for fatal CVD events. Because of the flexible and transparent nature of the model, it has many potential future applications. </AbstractSection> Copyright Springer International Publishing Switzerland 2013