This selection of Professor Dhrymes’s major papers combines important contributions to econometric theory with a series of well-thought out, skilfully executed empirical studies. The theoretical papers focus on such issues as the general linear model, simultaneous equations models, distributed lags and ancillary topics. Most of these papers originated with problems encountered in empirical research. The applied studies deal with production function and productivity topics, demand for labour, arbitrage pricing theory, demand for housing and related issues.