Bosmans, J.E.; Bruijne, M.C. de; Hout, H.P.J. van; … - 2008
An effective treatment already exists for many diseases. In these cases the effectiveness of a new treatment may be established by showing that the new treatment is as effective as (i.e., equivalent to) or at least as effective as (i.e., noninferior to) the old treatment. For an economic...