A methodology based on adaptive likelihood ratios (ALRs) for the detection of emerging disease clusters is presented. The martingale structure of the regular likelihood ratio is preserved by the ALR. The upper limit for the false alarm rate of the proposed method depends only on the quantity of...

Inference based on ratio of two independent Poisson rates is common in epidemiological studies. We study the performance of a variety of unconditional method of variance estimates recovery (MOVER) methods of combining separate confidence intervals for two single Poisson rates to form a...

Lagrange multiplier and Wald tests for the hypothesis of absence of unobserved confounding are extended to the context of semiparametric recursive and sample selection bivariate probit models. The finite sample size properties of the tests are examined through a Monte Carlo study using several...

A novel multivariate factor GARCH specification is used to obtain conditional covariance matrices of minimum variance portfolios containing a very large number of assets. The approach allows for time varying factor loads, and achieves great flexibility by allowing alternative specifications for...

The g-and-h distributional family is generated from a relatively simple transformation of the standard normal and can approximate a broad spectrum of distributions. Consequently, it is easy to use in simulation studies and has been applied in multiple areas, including risk management, stock...

A methodology is developed to add runs to existing supersaturated designs. The technique uses information from the analysis of the initial experiment to choose the best possible follow-up runs. After analysis of the initial data, factors are classified into one of three groups: primary,...

Models for survival data generally assume that covariates are fully observed. However, in medical studies it is not uncommon for biomarkers to be censored at known detection limits. A computationally-efficient multiple imputation procedure for modeling survival data with covariates subject to...

A parametric family of M-estimators of scale based on the Rousseeuw–Croux Qn-estimator is proposed; estimator’s bias and efficiency are studied. A low-complexity one-step M-estimator is obtained allowing a considerably faster computation with greater than 80% efficiency and the highest...

The following article considers a mixture of regressions with variable selection problem. In many real-data scenarios, one is faced with data which possess outliers, skewness and, simultaneously, one would like to be able to construct clusters with specific predictors that are fairly sparse. A...

Recently, the Dynamic Conditional Score (DCS) or Generalized Autoregressive Score (GAS) time series models have attracted considerable attention. This motivates the need for a software package to estimate and evaluate these new models. A straightforward to operate program called the Dynamic...