The phase II clinical trials often use the binary outcome. Thus, accessing the success rate of the treatment is a primary objective for the phase II clinical trials. Reporting confidence intervals is a common practice for clinical trials. Due to the group sequence design and relatively small...

Long-range-dependent time series are endemic in the statistical analysis of Internet traffic. The Hurst parameter provides a good summary of important self-similar scaling properties. We compare a number of different Hurst parameter estimation methods and some important variations. This is done...

Survival models involving frailties are commonly applied in studies where correlated event time data arise due to natural or artificial clustering. In this paper we present an application of such models in the animal breeding field. Specifically, a mixed survival model with a multivariate...

In many clinical studies, a commonly encountered problem is to compare the survival probabilities of two treatments for a given patient with a certain set of covariates, and there is often a need to make adjustments for other covariates that may affect outcomes. One approach is to plot the...

Heteroscedasticity checking in regression analysis plays an important role in modelling. It is of great interest when random errors are correlated, including autocorrelated and partial autocorrelated errors. In this paper, we consider multivariate <italic>t</italic> linear regression models, and construct the...

The traditional Cramér--von Mises criterion is used in order to develop a test to compare the equality of the underlying lifetime distributions in the presence of independent censoring times. Its asymptotic distribution is proved and a resampling plan, which is valid for unbalanced data...

Testing for the difference in the strength of bivariate association in two independent contingency tables is an important issue that finds applications in various disciplines. Currently, many of the commonly used tests are based on single-index measures of association. More specifically, one...

We aimed to study the excess health-care expenditures for persons with a known positive isolate of <italic>Streptococcus pneumoniae</italic>. The data set was compiled by linking the database of the largest Belgian Sickness Fund with data obtained from laboratories reporting pneumococcal isolates. We analyzed...

Permutation tests for symmetry are suggested using data that are subject to right censoring. Such tests are directly relevant to the assumptions that underlie the generalized Wilcoxon test since the symmetric logistic distribution for log-errors has been used to motivate Wilcoxon scores in the...