Peanut allergy is one of the most prevalent food allergies. The possibility of a lethal accidental exposure and the persistence of the disease make it a public health problem. Evaluating the intensity of symptoms is accomplished with a double blind placebo-controlled food challenge (DBPCFC),...

We analyze the multivariate spatial distribution of plant species diversity, distributed across three ecologically distinct land uses, the urban residential, urban non-residential, and desert. We model these data using a spatial generalized linear mixed model. Here plant species counts are...

To examine childhood cancer diagnoses in the province of Alberta, Canada during 1983--2004, we construct a generalized additive mixed model for the analysis of geographic and temporal variability of cancer ratios. In this model, spatially correlated random effects and temporal components are...

The semiparametric LABROC approach of fitting binormal model for estimating AUC as a global index of accuracy has been justified (except for bimodal forms), while for estimating a local index of accuracy such as TPF, it may lead to a bias in severe departure of data from binormality. We extended...

We propose a homogeneity test among groups on a quadratic distance measure. The underlying mutation process in the microsatellite loci is studied using the stepwise mutation model. Asymptotic normality of the test statistic is proved under very mild regularity conditions. Resampling methods,...

Three important and significantly heteroscedastic gross domestic product series are studied. Omnipresent heteroscedasticity is removed and the distributions of the series are then compared to normal, normal mixture and normal--asymmetric Laplace (NAL) distributions. NAL represents a skewed and...

We suppose a case is to be compared with controls on the basis of a test that gives a single discrete score. The score of the case may tie with the scores of one or more controls. However, scores relate to an underlying quantity of interest that is continuous and so an observed score can be...

In this paper, we study the change-point inference problem motivated by the genomic data that were collected for the purpose of monitoring DNA copy number changes. DNA copy number changes or copy number variations (CNVs) correspond to chromosomal aberrations and signify abnormality of a cell....