The main point of this paper is to show how ideas of control theory, automata theory and computer science can be applied to the field of oncology. We are stressing the modeling of three-dimensional tumor growth and the simulation of different kinds of tumor therapy (restricted energy supply,...

In effective planning a new water distribution system or enlarging an existing one we need to simulate the circumstances of the system on a computer and determine the best possible solutions. On the other hand if we have an existing water distribution system we want to run it as optimally as...

Computational fluid dynamics has many successes for the solution of simple standard problems. For relatively complex problems, especially if nonlinear and of mixed type, the computed approximate solutions are mostly of dubious accuracy and credibility. The difficulty appears fundamental. Model...

The identification problem for a system with a known structure is considered. The mathematical background of the identifiability problem is shortly discussed. Two minicomputer programs which have been used in several studies to solve the identifiability and the identification problem for...

Concept and brief description of major program modules for realization of general manipulation system “simulator”, i.e. programming system for the design, dynamic analysis, synthesis and verification of control algorithms for manipulation systems of arbitrary mechanical configuration is...

Numerous diverse mathematical models have been proposed, in an effort to explain and study the variety of aging processes which occur at the cellular level. This paper will detail the formalization of a framework for studying the propagation of a collection of biological properties through an...

EARLY DESIRE (Direct Executing SImulation in REal time) is the first of a series of entirely new floating-point equation-language systems for interactive continuous-system simulation. DESIRE systems combine high computing speed (1.3 to 4 times faster that threaded FORTRAN) with immediate direct...

A computer program is described for the determination of optimal multicompartmental sampling designs as a handle on numerical identifiability. A design measure approach is used which automatically chooses the number of sample times and sites of sampling. A two-input four-pool output example is...