NanoCarriers (nano-scaled structures loaded with an active substance) promise benefits for various fields of applications. First applications were established for medicinal products, applications for other fields are approaching (e.g., pesticides, biocides, cosmetics, food). NanoCarriers, which...

The overall aim of this scoping review was to explore the possible options for a tiered approach to bioaccumulation testing, the available tools or test methods, and to provide data to show potential linkages between the possible tiers in the testing strategy, as well as the evidence-base for...

Over the years, it became more and more evident that governmental considerations on new materials should not be limited to the ‘simple’ nanomaterials. Furthermore, many of these (nano) materials possess/display an additional complexity, e.g. a new or enhanced functionality and/or multiple...

The OECD’s Early Awareness and Action System for Advanced Materials (Early4AdMa) is a pre-regulatory and anticipatory risk governance approach for Advanced Materials. Early4AdMa help users (e.g., regulators) to identify potential issues of an advanced material, related to their safety,...

Technological innovations such as nanotechnology and/or biotechnology are being developed at such a rapid pace that they present a challenge to health and environmental risk assessment. Because of this rapid rate of innovation, a gap can arise between technological innovations and the...

This document provides the current practices, challenges and strategies for assessing risk of manufactured nanomaterials in circumstances where data is limited, and there is a necessity for more research on specific risk assessment issues. As such, the document presents an overview of the...

This report contains the performance testing results of the selected tools after assessment of scope, accessibility and support, and sensitivity analysis. From the first initial list, which included 23 occupational exposure assessment tools (13 nanospecific and 10 conventional chemical tools),...

The project “Compilation of Available Tools and Models Used for Assessing Consumer Exposure to Manufactured Nanomaterials and Evaluation of their Applicability in Exposure Assessments” aimed to (1) compile the available tools and models for assessing consumer exposure to Manufactured...

The objective of this report is to compile available tools and models for the assessment of environmental exposure to manufactured nanomaterials, and to conduct an analysis of their applicability for use in regulatory exposure assessment. The report assesses the compiled models by providing a...

This document provides a compilation of 32 models/tools, 9 of which were assessed under the occupational project, 9 under the consumer project, and the remaining 14 under both projects. The compilation of the models/tools was created by consultation within the OECD and by searching in several...