A variety of complications arise when imperfect measurements, W, are observed in place of a true variable of interest, X. In the context of linear and non-linear regression models where X is a covariate, regression parameter estimators obtained when W is substituted for X may be substantially...

We propose a new procedure for estimating the survival function of a time-to-event random variable under arbitrary patterns of censoring. Under mild smoothness assumptions, this procedure allows a unified approach to handling different kinds of censoring, while in many cases increasing...

Count data with excess zeros are commonly seen in experiments forimproving electronics manufacturing quality, in medical researchof HIV patients with high-risk behaviors and in agricultural study of number of insects per leaf.Yip (1988) and Lambert (1992) proposed zero-inflated Poisson...

In many clinical trials related to diseases such as cancers and HIV, patients are treated by different combinations of therapies. This leads to two-stage designs, where patients are initially randomized to a primary therapy and then depending on disease remission and patients' consent, a...

In many clinical trials related to diseases such as cancers and HIV, patients are treated by different combinations of therapies. This leads to two-stage designs, where patients are initially randomized to a primary therapy and then depending on disease remission and patients' consent, a...