Extensions of Simple Component Analysis are proposed. Two methods are obtained: a new Simple Component Analysis and a Simple Linear Discriminant Analysis. These two methodologies use Genetic Algorithms, optimize a criterion (derived from the usual method) and add constraints. The objective is to...

Mass spectrometry from clinical specimens is used in order to identify biomarkers in a diagnosis. Thus, a reliable method for both feature selection and classification is required. A novel method is proposed to find biomarkers in SELDI-TOF in order to perform robust classification.The feature...