Understanding the relationship between the disease-specific health status measurement (the National Eye Institute Vision Function Questionnaire, NEI-VFQ 25) and the health utility index derived from the EQ-5D will inform researchers of which aspects of vision functioning they should focus on to...

The CLBP-IQ was developed in accordance with current US Food and Drug Administration guidance on instrument development. Results from both concept elicitation and cognitive debriefing interviews support the content validity of the CLBP-IQ in patients with CLBP. Future development should proceed...

Introduction / Irina Farquhar, Kent Summers and Alan Sorkin -- After-market drug regulation : promoting public trust in innovation / Robert Field -- Transcending tradition : quality of life as the inextricable link between activities of daily living and specific organ and disease states / Etta...

Where is the Life we have lost in living?Where is the wisdom we have lost in knowledge?Where is the knowledge we have lost in information? Thomas Stearns Eliot. This book is a collection of multi-author contributed research devoted to exploring the synergy of new science-based health-risks...

The U.S. healthcare system is very complex and inundated with many challenges, ranging from escalating healthcare expenditure to increasing prevalence of medication errors. Emphasis on cost reduction and prevention of medication errors has given impetus to the development of computerized...

This chapter proposes an optimized innovative information technology as a means for achieving operational functionalities of real-time portable electronic health records, system interoperability, longitudinal health-risks research cohort and surveillance of adverse events infrastructure, and...

We study changes in age-specific diabetes-related mortality and annual health care utilization. We find that half of the estimated 16% increase of diabetic mortality falls within employable age groups. We estimate that disease combination-specific increase in case fatality has resulted in...

The study considers annual health care utilization and costs associated with human immunodeficiency virus (HIV) infection and the autoimmune disease syndrome (AIDS) complex by applying the previously developed disease and disease combination-specific cost of illness methodology. This study...