We focus on the D-optimal design of screening experiments involving main-effects regression models, especially with large numbers of factors and observations. We propose a new selection strategy for the coordinate-exchange algorithm based on an orthogonality measure of the design. Computational...

In many industrial experiments, some of the factors are not independently reset for each run. This is due to time and/or cost constraints and to the hard-to-change nature of these factors. Most of the literature restricts the attention to split-plot designs in which all the hard-to-change...

The responses obtained from response surface designs that are run sequentially often exhibit serial correlation or time trends. The order in which the runs of the design are performed then has an impact on the precision of the parameter estimators. This article proposes the use of a...