Search Results - subject:"Designability"

Did you mean: subject:"desirability" (316 results)

Thermodynamic analysis of protein sequence-structure relationships in monomer and dimer forms

Li, Z.R.; Liu, G.R.; Cheng, Y. - In: Physica A: Statistical Mechanics and its Applications 354 (2005) C, pp. 381-392

Two-dimensional lattice model is employed to analyze the sequence–structure relationships between HP and YhHX protein sequences and compact structures in monomer and homodimer forms. Our results show that most structures are encoded by normal and prion protein sequences, and about one-third of...

Persistent link: https://www.econbiz.de/10010589639

Simple models of the protein folding problem

Tang, Chao - In: Physica A: Statistical Mechanics and its Applications 288 (2000) 1, pp. 31-48

will give an introduction to the problem, and then focus on some recent work concerning the so-called “designability … principle”. The designability of a structure is measured by the number of sequences that have that structure as their unique … ground state. Structures differ drastically in terms of their designability; highly designable structures emerge with a …

Persistent link: https://www.econbiz.de/10011061498