Over the last decade, real spending in the United Kingdom NHS doubled in real terms to meet government targets including moves to increase spending rates to other EU countries and increasing health demands both as a result of increasing population of the elderly and illness related to lifestyle....

Global climate change is one of the highest concerns in the scientific, health and environmental arena. Establishing association between weather and health exposures are fundamental to learn about the complex exposure-disease relationship but the link between them are still largely unexplored....

In the context of Grid computing, reputation-based trust management systems are playing an increasingly important role for supporting coordinated resource sharing and ensuring provision of quality of service. However, the existing Grid reputation-based trust management systems are considered...

Enterprise business models and the semantic of their dynamic changes are influenced a) by internal factors which dictate the nature and the role of business processes within the enterprise and b) by the external factors which live in enterprise’s environment, such as technological changes,...

The advantages a DSL and the benefits its use potentially brings imply that informed decisions on the design of a domain specific language are of paramount importance for its use. We believe that the foundations of such decisions should be informed by analysis of data empirically collected from...

The concept of trust and reputation had a long profound impact on the way systems were measured in terms of their credibility and performance. This has consecutively lead into numerous reputation-based trust management systems being deployed for various computing environments as a decision...

The complex procedure of processing the marketing authorization of medicinal product licenses is a challenging task for government health authorities and the pharmaceutical industry across the world. Regulatory requirements have diverged significantly, and each country has its own regulations...

Discrete event simulation modelling has been extensively used in modelling complex systems. Although it offers great conceptual-modelling flexibility, it is both computationally expensive and data intensive. There are several examples of simulation models that generate millions of observations...