Search Results - subject:"Genotyping error"

Estimating genotyping error rates from parent–offspring dyads

Haaland, Øystein A.; Skaug, Hans J. - In: Statistics & Probability Letters 83 (2013) 3, pp. 812-819

A common approach when estimating the error rate of a DNA register is to genotype some of the individuals twice. This may be both expensive and time consuming. As an alternative, we present a new method for estimating genotyping errors based on parent–offspring dyads. The basic idea is that...

Persistent link: https://www.econbiz.de/10011039794

Increase of Rejection Rate in Case-Control Studies with the Differential Genotyping Error Rates

Ahn, Kwangmi; Gordon, Derek; Finch, Stephen - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 25-25

Genotyping error adversely affects the statistical power of case-control association studies and introduces bias in the … size increases for fixed differential genotyping error rates and nominal significance level for each test. …

Persistent link: https://www.econbiz.de/10005046594

Incorporating Duplicate Genotype Data into Linear Trend Tests of Genetic Association: Methods and Cost-Effectiveness

Borchers, Bryce; Brown, Marshall; McLellan, Brian; … - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 24-24

acquisition costs is less than or equal to the genotyping error rate it is more powerful to duplicate genotype the entire sample …

Persistent link: https://www.econbiz.de/10005046603