Measurement of the amount of oxidative damage to DNA is one tool that can be used to estimate the beneficial effect of diet on the prevention of colon carcinogenesis. The FLARE assay is a modification of the single-cell gel electrophoresis (Comet) assay, and provides a measure of the 8OHdG...

Advances in computation mean that it is now possible to fit a wide range of complex models to data, but there remains the problem of selecting a model on which to base reported inferences. Following an early suggestion of Box & Tiao, it seems reasonable to seek 'inference robustness' in reported...

The authors study alternative estimators of the impacts of higher level variables in multilevel models. This is important since many of the important variables in social science research are higher level factors having impacts on many lower level outcomes such as school achievement and...

We describe a new and flexible framework for modeling school effects. Like previous work in this area, we introduce an empirical model that evaluates school performance on the basis of student level test-score gains. Unlike previous work, however, we introduce a flexible model that relates...

We consider the problem of adjusting a machine that manufactures parts in batches or lots and experiences random offsets or shifts whenever a set-up operation takes place between lots. The existing procedures for adjusting set-up errors in a production process over a set of lots are based on the...

We propose and compare two approaches for regression analysis of multilevel binary data when clusters are not necessarily nested: a GEE method that relies on a working independence assumption coupled with a three-step method for obtaining empirical standard errors; and a likelihood-based method...

This article describes an extension of classical x 2 goodness-of-fit tests to Bayesian model assessment. The extension, which essentially involvesevaluating Pearson's goodness-of-fit statistic at a parameter value drawn from its posterior distribution, has the important property that it is...