Purpose: Value-based pricing of new, innovative health technologies defined as pricing through economic evaluation requires the use of a basic cost-effectiveness threshold. This study presents a cost-effectiveness model that determines the cost-effectiveness threshold for life-extending new,...

Background: The American College of Surgeons Oncology Group Z0011 trial showed that complete axillary lymph node dissection (cALND) did not improve survival benefits in patients with one or two tumour-involved sentinel lymph nodes and undergoing breast conservation. Still, a considerable number...

Purpose: Oncology drugs are often approved for multiple indications, for which their clinical benefit varies. Aligning a single price to this differing value remains a challenge. This study examines the clinical and economic value, price, and reimbursement of multi-indication cancer drugs across...

Consumer eHealth is becoming a fundamental component of health care. However, only provisional steps have been made to increase our understanding of how consumers engage with eHealth. We undertook an interpretive review to assess the evidence about consumer use of eHealth. We identified five...

Summary We evaluated the cost-effectiveness of a fractureliaison service prospectively designed to have a parallelcontrol group treated by standard care. The clinicaleffectiveness of this service was associated with anincremental cost-effectiveness ratio versus standard care ofAustralian dollars...

Thoroughbred jumps racing jockeys have a fall rate greater than their flat racing counterparts. Previous studies have focused on factors that contribute to falls by horses but, to date, there has not been a study of risk factors for falls to jockeys in jumps races. Data on race-day falls were...

Background: This paper estimates the economic impact of HIV/AIDS on the KwaZulu-Natal province and the rest of South Africa. Methods: We extended previous studies by employing: an integrated analytical framework that combined firm surveys of workers' HIV prevalence by sector and occupation; a...

Traders in the financial world are assessed by the amount of money they make and, increasingly, by the amount of money they make per unit of risk taken, a measure known as the Sharpe Ratio. Little is known about the average Sharpe Ratio among traders, but the Efficient Market Hypothesis suggests...

Objective : Examine the cost of healthy food habits for welfare-dependent families in Australia. Method :  A seven-day meal plan was developed, based on Australian public health recommendations, for two typical welfare-dependent families: a couple-family (two adults, two children) and a...

This study addresses the ongoing implications of the realignment of the pharmaceutical industry knowledge base ? from small molecule methods to new biomedical technologies ? for the competitive positions of traditional pharmaceuticalcompanies and biopharmaceutical start-ups. The theoretical...