Chagas disease is one of the most important neglected tropical diseases. Endemic in Latin America, the disease is a global public health problem, affecting several countries in North America, Europe, Asia and Oceania. The disease affects around 8-10 million people worldwide and the limited...

It has been a decade since the introduction of the MIA-QSAR (acronym of Multivariate Image Analysis applied to Quantitative Structure Activity Relationship) method. While many successes have been achieved over the years, the path for the progressive development of this method has been far from...

The inhibition effect of synthesized N′-(phenylmethylidene)-2-(2-methyl-1H-benzimidazol-1-yl)acetohydrazides, N′-(4-methylphenylmethylidene)-2-(2-methyl-1H-benzimidazol-1-yl)acetohydrazides, and N′-(4-methoxyphenylmethylidene)-2-(2-methyl-1H-benzimidazol-1-yl)acetohydrazides on the...

The three-dimensional structures of surfactant-like peptides containing 4–10 glycines as the components of the hydrophobic tails and aspartic acids as the hydrophilic heads (G4D2, G6D2, G8D2, G10D2) are investigated by using the multicanonical simulation procedure. The thermodynamically most...

The exact analytical result for a class of integrals involving (associated) Legendre polynomials of complicated argument is presented. The method employed can in principle be generalized to integrals involving other special functions. This class of integrals also proves useful in the...