Abstract Purpose: The nested case–control study design, in which a fixed number of controls are matched to each case … distribution on the bias and relative efficiency of the conditional likelihood estimator from a nested case–control study. Methods …

The nested case-control (NCC) design is widely used in epidemiologic studies as a cost-effective subcohort sampling …

case-control design.A nested case-control study is "nested" within a cohort study such that both cases and controls are … selected from within a defined cohort. A nested case-control design is more cost-efficient than a full cohort study since … risk of a cohort from measures only taken on the nested case-control participants. The proposed method is evaluated using …