We are concerned with the simulation and optimization of large-scale gas pipeline systems in an error-controlled environment. The gas flow dynamics is locally approximated by sufficiently accurate physical models taken from a hierarchy of decreasing complexity and varying over time. Feasible...

Hammerstein–Wiener models constitute a significant class of block-structured dynamic models, as they approximate process nonlinearities on the basis of input–output data without requiring identification of a full nonlinear process model. Optimization problems with Hammerstein–Wiener models...

We present a theory of human capital, with its two most essential components, health capital and, what we term, skill capital, endogenously determined within the model. Using the theory, and a calibrated version of it, we uncover and highlight an important economic mechanism driving...

We investigate the effect of a miscarriage on mental health care use, labour market and family outcomes of women and their partners using Dutch linked ad- ministrative data. Miscarriages are common and largely random conditional on age. We estimate event study models using women with a completed...

We propose and solve an optimal vaccination problem within a deterministic compartmental model of SIRS type: the immunized population can become susceptible again, e.g. because of a not complete immunization power of the vaccine. A social planner thus aims at reducing the number of susceptible...