As part of the evaluation of the American Recovery and Reinvestment Act (ARRA) investment in comparative effectiveness research (CER), Mathematica developed a conceptual framework to guide future efforts to assess the impact of CER. In addition, we explored methodological challenges related to...

Objective: This study aimed to apply the previously validated severity index for rheumatoid arthritis (SIFRA) to prevalent rheumatoid arthritis (RA) groups in Turkey and determine the effect of RA severity on health care costs and biologic use. Methods: This retrospective study used the Turkish...

Steven SimoensResearch Centre for Pharmaceutical Care and Pharmaco-economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumAbstract: Given that biosimilars are agents that are similar but not identical to the reference biopharmaceutical, this study aims to...

Xiaomei Peng1, Haya Ascher-Svanum1, Douglas E Faries1, Virginia L Stauffer1, Sara Kollack-Walker1, Bruce J Kinon1, John M Kane21Eli Lilly and Company, Indianapolis, Indiana; 2Zucker Hillside Hospital, Department of Psychiatry, Glen Oaks, New York, USABackground: To compare the cost-effectiveness...

Rikke Søgaard1, Jan Sørensen1, Louise Linde2, Merete L Hetland2,31CAST – Centre for Applied Health Services Research and Technology Assessment, University of Southern Denmark, Denmark; 2Department of Rheumatology, Hvidovre and Glostrup Hospitals, Denmark; 3The DANBIO registry, Hvidovre and...

John E Goulionis1, Athanassios Vozikis2, VK Benos1, D Nikolakis11Department of Statistics and Insurance Science, University of Piraeus, Piraeus, Greece; 2Department of Economic Science, University of Piraeus, Piraeus, GreeceObjective: To assess the cost-effectiveness of two treatments (medical...

Esther CuboNeurology Department, Hospital General Yagüe, Burgos, SpainAbstract: In the absence of a cure, the primary goals in managing Parkinson’s disease (PD) are to preserve functionality and health-related quality of life (HRQoL). Current therapeutic strategies for PD include symptomatic...