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Permutation of regressor residuals test 1 Predictive biomarkers 1 Treatment-by-gene interaction 1
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Benner, A. 1 Kopp-Schneider, A. 1 Werft, W. 1
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Computational Statistics & Data Analysis 1
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On the identification of predictive biomarkers: Detecting treatment-by-gene interaction in high-dimensional data
Werft, W.; Benner, A.; Kopp-Schneider, A. - In: Computational Statistics & Data Analysis 56 (2012) 5, pp. 1275-1286
For personalised medicine the identification of predictive biomarkers is of great interest. These could guide the choice of therapy and could therefore optimise the benefits of patients of such treatments. The technology of gene expression microarrays allows one to scan thousands of potentially...
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