This paper proposes a method for the on-line determination of the concentration profiles in a Simulated Moving Bed (SMB) process in terms of discrete measurement values. A direct solution of this state observation problem is very complex because the physical SMB model exhibits the infinite state...

Chromatographic separation processes are an emerging technology, especially in the field of fine chemicals and pharmaceutical products. As an alternative to conventional batch chromatography, the simulated moving bed (SMB) process gained more and more impact recently. Because of the complex...