N-Acetyltransferase 2 (NAT2) genotyping may result in a considerable percentage in several ambiguous allele combinations. PHASE 2.1 is a statistical program which is designed to estimate the probability of different allele combinations. We have investigated haplotypes of 2088 subjects genotyped...

Interactions of single nucleotide polymorphisms (SNPs) are assumed to be responsible for complex diseases such as sporadic breast cancer. Important goals of studies concerned with such genetic data are thus to identify combinations of SNPs that lead to a higher risk of developing a disease and...

N-Acetyltransferase 2 (NAT2) genotyping may result in a considerable percentage in several ambiguous allele combinations. PHASE 2.1 is a statistical program which is designed to estimate the probability of different allele combinations. We have investigated haplotypes of 2088 subjects genotyped...

Interactions of single nucleotide polymorphisms (SNPs) are assumed to be responsible for complex diseases such as sporadic breast cancer. Important goals of studies concerned with such genetic data are thus to identify combinations of SNPs that lead to a higher risk of developing a disease and...

The issue of suitable similarity measures for a particular kind of genetic data - so called SNP data - arises, e.g., from the GENICA (The Interdisciplinary Study Group on Gene Environmental Interactions and Breast Cancer in Germany) case-control study of sporadic breast cancer. The GENICA study...

The issue of suitable similarity measures for a particular kind of genetic data - so called SNP data - arises, e.g., from the GENICA (The Interdisciplinary Study Group on Gene Environmental Interactions and Breast Cancer in Germany) case-control study of sporadic breast cancer. The GENICA study...