For cancer, we develop a 2-D agent-based continuous-space game-theoretical model that considers cancer cells' proximity to a blood vessel. Based on castrate resistant metastatic prostate cancer (mCRPC), the model considers the density and frequency (eco-evolutionary) dynamics of three cancer...

For cancer, we develop a 2-D agent-based continuous-space game-theoretical model that considers cancer cells’ proximity to a blood vessel. Based on castrate resistant metastatic prostate cancer (mCRPC), the model considers the density and frequency (eco-evolutionary) dynamics of three cancer...

Cooperation among self-interested individuals pervades nature and seems essential to explain several landmarks in the evolution of live organisms, from prebiotic chemistry through to the origins of human societies. The iterated Prisoner's Dilemma (IPD) has been widely used in different contexts,...