Under physiological conditions, hemoglobin (Hb) and myoglobin (Mb) are subject to autoxidation, leading to the formation of ferric heme proteins with weakened globular structures and resulting in the loss of the heme cofactor. To gain further insights into the role of the heme pocket in the...

We study two dimensions of complexity that may interfere with individual choice. The first one is object complexity, which corresponds to the difficulty of evaluating any given alternative in the choice set. The second dimension is composition complexity, which increases when suboptimal...

This article examines innovation in megaprojects and the way in which project complexity plays a role in innovation. Megaprojects are experiencing increasing levels of innovation as a means to deal with complexity and to improve the delivery of megaprojects. So far the relation between...

The diethylphosphonate ligand HL 1 substituted pyridylpyrrole was synthesized by treatment of 2-bromo-6-(1H'-pyrrol-2-yl)pyridine and diethylphosphite in presence of base triethylamine and catalyst Pd(PPh 3 ) 4 under refluxing toluene conditions. The HL 1 ligand was treated with...

This paper provides a characterization of the dynamic interactions in the VIX complex, composed of the VIX itself, the term structure of VIX futures, and VIX ETPs. I investigate a model that summarizes the VIX futures term structure using latent factors (level, slope, and curvature) and expand...

This paper explores the impact of digital technologies on the nature and routine intensity of shopfloor work, the ways in which digital technologies exert their effects and the factors moderating the outcomes of digitalisation in respect of work.The effect of technology cannot be limited to a...

Complex agriculture projects directly affect the welfare of over half the world’s population, are a key Sustainable Development Goal (SDG), and account for the single most extensive human activity across 40% of the world’s surface. Furthermore, they are highly susceptible to environmental,...

This chapter reviews recent advances in the NK modeling literature conceptualizing organizational change and innovation as a search over a complex landscape. It discusses both strengths and limitations of this perspective and delineates potential for future research directions. The key argument...

We study two dimensions of complexity that may interfere with individual choice. The first one is object complexity, which corresponds to the difficulty in evaluating any given alternative in a choice set. The second dimension is composition complexity, which increases when suboptimal...