Mullins, C. Daniel.; Whicher, Danielle; Reese, Emily S.; … - In: PharmacoEconomics 28 (2010) 10, pp. 969-976
Comparative effectiveness research (CER), or research design to meet the needs of post-regulatory decision makers, has … inform the design of these clinical trials. Historically, without explicit FDA guidance, broad patient populations, including … women and minorities, often were not considered in trial design. In addition, attempts to minimize cost and maximize …