Yuan, Min; Tian, Xin; Zheng, Gang; Yang, Yaning - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 30-30
optimal for an additive genetic model. Other TDT-type tests optimal for recessive and dominant models have also been developed … flexable family-based association tests (FBAT). TDT-type tests have high efficiency when the genetic model is known or … correctly specified, but may lose power if the model is mis-specified. Hence tests that are robust to genetic model mis …